The Kassam Stadium will host Oxford United Ladies for the first time later this month.
The ground will stage the FA Women’s Cup fourth-round tie against Newcastle United Ladies after causing the shock of the third round last weekend with a 2-1 win at Charlton Athletic.
Manager Richard Blackmore said: “It’s a fantastic opportunity for the girls to show what they can do and it is very exciting to be playing at the Kassam Stadium.
“They have had such a great season and this is another sign that we are progressing.”
The game will be played on Sunday, February 24, 1pm kick-off. Admission will be £5 adults and £3 for under 16s.