Lock Owen Fowler and wing Lewis Collins both miss Witney’s home derby with Bicester in Southern Counties North on Saturday due to injury.
Tom Overbury replaces Collins for the leaders, while Joe Rowles returns after injury in the second row, with Richard Kerr and Aaron Lambourne slotting in on the bench.
Grove go one better than last week by fielding five sets of brothers at Amersham & Chiltern.
Full back John Barrett returns to play alongside his brother James, who starts at scrum half, while the Seviers, Nicholls, Maryons and Elthams complete the quintet.
Grove (v Amersham & Chiltern, away): John Barrett, Harrington, N Sevier, D Maryon, Grant, R Sevier, James Barrett, T Eltham, G Eltham, Keen, S Maryon (capt), Weaving, Fredericks, G Nicholl, B Nicholl. Reps: North, Kerr, Gerring.
Witney (v Bicester, home): Mitchem, Overbury, Strutt, J Lamb (capt), Monks, H Lamb, G Campbell, Griffiths, S Collins, Richens, Rowles, Bennett, Caffekey, Muller, C Campbell. Reps: Serle, Kerr, Lambourne.
Oxford Harlequins 2nd (v Wallingford 2nd, away, meet 12.45pm).
Oxford Harlequins 3rd (v Aylesbury Athletic, away, meet 12.45pm).
Oxford Harlequins 4th (v Marlow 4th, away, meet 12.45pm).
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