Seventeen people were taken to hospital after an Oxford Tube coach carrying 35 passengers overturned.
Four of the casualties had surgery for injuries including broken bones, with 13 others needing other treatment after the crash just off the M40 at Thame.
The double-deck vehicle flipped on its side just before 11pm yesterday on the north-bound slip at junction seven.
All the casualties were taken to John Radcliffe Hospital in Oxford, and several have already been discharged.
Thames Valley Police said no other vehicle was involved in the incident, and it is not yet known what caused the crash.
Police closed the slip road while they investigated what happened, but the motorway remained open in both directions.
Six ambulances from South Central Ambulance Service attended the crash scene.
"The hospital is working well with its partners and relatives are being contacted," a spokeswoman for John Racliffe said.
Were you on the coach? Call the newsdesk on 01865 425500 or email your pictures to yourpix@oxfordmail.co.uk.
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