OXFORD University will face the Barbarians to celebrate their 150th anniversary season.
The fixture against the world-famous invitational side takes place at Iffley Road on Saturday, May 16.
It is part of a double header to conclude the club's milestone year, with the Women's Blues facing invitational team Penguin International RFC earlier in the day.
The squad for the Barbarians' fixtures last autumn included former Ireland captain Rory Best and South African World Cup winner Schalk Brits.
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