THE A34 southbound is closed between the Chilton Interchange and junction 13 of the M4.
Nearly six miles of queues have formed after a crash between two lorries at 2.30am led to a diesel spill, which is currently being cleaned up.
A Highways Agency spokesman said the road was expected to reopen at around 8.30am.
In the meantime he advised travellers to find an alternative route.
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