Both lanes of the A40 near Eynsham have been closed, following a crash involving at least three vehicles.
The accident happened at Barnard Gate just after 8am and left at least two people injured police said.
The road is expected to remain closed for the rest of the morning.
Check back for updates.
Comments: Our rules
We want our comments to be a lively and valuable part of our community - a place where readers can debate and engage with the most important local issues. The ability to comment on our stories is a privilege, not a right, however, and that privilege may be withdrawn if it is abused or misused.
Please report any comments that break our rules.
Read the rules hereComments are closed on this article