Agnes Court residents welcomed back friends from Oxford University rugby teams to play ping-pong.
The university students chatted to residents about the recent World Cup defeat and volunteers at the care home said 'everyone had a blast'.
Home to 24 adults, the establishment is part of Leonard Cheshire charity that supports people with disabilities.
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Matt Barton, 20, one of the occupants, said: "We really enjoyed chatting to the players, talking about rugby and many other things.
It was a brilliant day."
Rugby captain, Ed David, 24, said: "It was really good to talk to everyone, and spend quality time with people.
We'll see some of the guys at Twickenham for the Varsity Match".
This year's Varsity Match will take place on December 12 at Twickenham where the team will face off their big rivals Cambridge.
The event is expected to attract huge crowds and the charity is set to benefit from funds raised at the games.
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Leonard Cheshire customers from Agnes Court and around the UK will be joining the players in London to watch the Varsity Match.
Previously, the two teams have welcomed the rugby fans from the care home to their matches at Iffley Road.
The women's game kicks-off at 11.30am, swiftly followed by the men's at 3pm.
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