Mid Oxon bowed out of the ESFA Under 15 PlayStation Inter Association Trophy with a 3-1 defeat by Southampton in the third round at Marlborough School, Woodstock.
Southampton took the lead after 22 minutes when Sam Woodward fired home a shot from outside the penalty area.
Mid Oxon fell further behind in the second half as Harry Harris’s effort flew over goalkeeper Martin Watrob’s outstretched hands.
But the hosts pulled a goal back when a well-worked move down the right was finished off by Marcus Smith at the far post with a left-foot shot.
Mid Oxon had several chances to equalise, but Southampton clinched victory when Woodward grabbed his second in the 65th minute.
OXFORDSHIRE take on Kent in the ESFA Under 14 PlayStation Inter County Trophy first round at Milton United on Saturday (11am).