The A40 has reopened after being shut in both directions after a crash involving four vehicles.
The accident occurred at the Wolvercote Roundabout.
Thames Valley Police were called at 10.26am.
A Thames Valley Police spokesman said injuries are not thought to be fatal at this stage.
The force confirmed the incident involved a white DAF Truck, Ford transit and a Ford Focus car and an unidentified car.
The A40 was closed at the roundabout for several hours following the collision but has now been reopened.
Our top stories:
8:29am Friday 22nd May 2015
A HOUSE fire that forced people to jump for their lives was started by a businessman who accused his best man of having an affair with his wife, a jury heard.
3:16pm Friday 22nd May 2015
A WOMAN who went missing from Banbury has been found, police said
3:24pm Friday 22nd May 2015
TRAINS from Oxford could be disrupted after a person was hit by a train between Slough and Reading.
3:23pm Friday 22nd May 2015
TWO teenagers have been arrested after a robbery in Hythe Bridge Street.
9:30am Friday 22nd May 2015
Ryan Taylor remains firmly on Oxford United’s radar despite the signing of Kemar Roofe, according to head coach Michael Appleton.
7:54am Friday 22nd May 2015
ALL LANES have reopened on the A4165 Oxford Road after a earlier incident involving a broken down van.