CAMPAIGNERS last night demanded action to make the A34 safer after the three-year-old girl involved in the crash at Hinksey Hill died in hospital.

Police confirmed she died from critical injuries on Saturday, following the multi-vehicle crash on the northbound carriageway two days before.

Her 31-year-old mother, from Hampshire, is still being treated at the John Radcliffe Hospital and is said to be stable.

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Thames Valley Police yesterday confirmed that a 58-year-old man was arrested on suspicion of causing serious injury by dangerous driving and bailed until October 2.

Investigating officer Sgt Beth Walton said: "This was a very serious incident and we are continuing to appeal for anyone who may have witnessed the incident to come forward."

The girl's death came just two weeks after a mother and three other children were killed in a crash on the A34 near Chilton.

The number of deaths on the road this year has now risen to six, one less than the last five years combined.

It sparked calls for fresh speed restrictions and signs to warn drivers about the number of fatalities on the road, with MPs calling for an urgent meeting with Roads Minister John Hayes.

A spokesman for Highways England – which manages the A34 – insisted safety was its top priority and said new studies of safety issues had been launched.

But last night A34 Action Group spokeswoman Cathryn Millward said changes were needed "immediately".

She added: "It is incredibly sad we have now seen six people die on the A34 this year.

"We need to start looking at how to make this road safer as soon as possible and in the meantime put in place safety measures.

"We cannot wait any longer. People need to see something is being done."

Her comments came as almost 2,300 people had signed a petition on Change.org, calling for 50mph speed limits on the carriageway with enforcement cameras.

Alongside the three-year-old girl and her mother, 11 others were injured in the latest smash at Hinksey Hill on Thursday night.

Oxfordshire County Council said the girl who died was believed to be the youngest fatality on the A34 in Oxfordshire since August 24, 1995 - almost 21 years to the day - when a two-year-old was killed in a collision near Pear Tree.

She is also the second-youngest person to die since records began in 1979.

Yesterday Oxfordshire's MPs said they would meet next week to discuss how to lobby the Government for safety improvements.

Oxford East MP Andrew Smith said: "This very sad death, coming on top of the other awful fatalities on this road, underline the need for an urgent review of safety all along the A34."