The A40 has reopened after being shut in both directions after a crash involving four vehicles.
The accident occurred at the Wolvercote Roundabout.
Thames Valley Police were called at 10.26am.
A Thames Valley Police spokesman said injuries are not thought to be fatal at this stage.
The force confirmed the incident involved a white DAF Truck, Ford transit and a Ford Focus car and an unidentified car.
The A40 was closed at the roundabout for several hours following the collision but has now been reopened.
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