A 27-year-old woman is fighting for her life in hospital after a car crash which injured three others including two children.
The A329 was closed both ways for nearly three hours following the two-car collision between Great Milton and Stadhampton shortly before 10am.
One person also had to be cut from the wreckage by firefighters.
Thames Valley Police spokeswoman Lucy Billen said the black Ford Focus and black Volkswagen Golf were travelling in opposite directions before the collision.
She said the 27-year-old woman, who was driving the Ford Focus, was in a critical condition and the driver of the Golf, a woman aged 47, and her two 12-year-old passengers were also taken to the John Radcliffe Hospital in Oxford.
South Central Ambulance Service spokeswoman Michelle Archer said paramedics were called to the crash scene at about 9.45am.
She added that the air ambulance was sent along with four ambulance crews, a rapid response vehicle and two ambulance officers.
Comments: Our rules
We want our comments to be a lively and valuable part of our community - a place where readers can debate and engage with the most important local issues. The ability to comment on our stories is a privilege, not a right, however, and that privilege may be withdrawn if it is abused or misused.
Please report any comments that break our rules.
Read the rules hereComments are closed on this article